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Exposome Geocoder – Input Preparation and Usage Guide

Note: This toolkit does not share any Protected Health Information (PHI).

This repository provides a reproducible workflow to geocode patient location data (Phase 1) and link the resulting coordinates with exposome datasets (Phase 2). This workflow ensures that sensitive address data remains local while generating standardized exposure metrics to be shared to central server without identifiers.

This SOP describes the workflow for running codes to geocode patient location data and link latitude and longitude coordinates with exposome datasets. All code will be executed locally at each site. Only the exposure tables containing exposome data will be shared with the central server; no address-level data will be transmitted or stored centrally. Sites should use the most granular address information available to them or latitude/longitude coordinates.

Demo video Watch here


📑 Table of Contents


Overview

This workflow uses two separate Docker containers to support end-to-end geocoding and data linkage:

  1. Exposome Geocoder Container (prismaplab/exposome-geocoder:1.0.4)
    Performs address or coordinate-based geocoding to generate latitude/longitude for LOCATION workflows and supports FIPS workflows when needed, using DeGAUSS backend tools.
  2. Exposome Linkage Container (ghcr.io/chorus-ai/chorus-postgis-exposure:main)
    Integrates the geocoded outputs with relevant environmental and social determinant datasets to produce analysis-ready files.

Together, these containers enable:

  • Address and latitude/longitude-based geocoding
  • LOCATION and LOCATION_HISTORY preparation for linkage
  • OMOP CDM geocoding extraction and processing
  • GIS linkage with PostGIS-SDoH indices (ADI, SVI, AHRQ)

Input Options

Phase 1 (Geocoding) Input: To generate coordinates, you need to prepare only ONE of the following data elements per encounter (Option 1: Address, Option 2: Coordinates, or Option 3: OMOP CDM tables).

Phase 2 (Linkage) Input: Regardless of the input option chosen for Phase 1, the final output MUST be transformed into two specific CSV files to run Phase 2.

  • LOCATION.csv: Contains the physical coordinates (latitude, longitude) and identifiers (location_id).
  • LOCATION_HISTORY.csv: Contains the temporal mapping of a person (entity_id, which is same as person_id) to a location (location_id) over a specific time range (start_date, end_date).

See Appendix A for the Data Dictionary and population logic.

Option 1: Address

Sample input files here

  • Format A: Multi-Column Address
streetcitystatezipyearentity_id
1250 W 16th StJacksonvilleFL3220920191
2001 SW 16th StGainesvilleFL3260820192

Tip: Street and ZIP are required. Missing these fields may lead to imprecise geocoding.

  • Format B: Single Column Address
addressyearentity_id
1250 W 16th St Jacksonville FL 3220920191
2001 SW 16th St Gainesville FL 3260820192

Optional Supporting Files

Including the following optional files will help streamline the end-to-end workflow between geocoding and exposome linkage:

  • Important: Do not date-shift your LOCATION/LOCATION_HISTORY files before linkage. Date shifting (if used) should occur post linkage in Step 4.

  • LOCATION.csv

  • LOCATION_HISTORY.csv

If these files are provided during geocoding, the output will automatically include the updated latitude and longitude information required for the postgis linkage container.

If they are not provided, users will need to manually update their LOCATION files with the geocoded latitude/longitude before executing the commands for linkage.

LOCATION.csv (Follows CDM format)
location_idaddress_1address_2citystatezipcountylocation_source_valuecountry_concept_idcountry_source_valuelatitudelongitude
11248 N Blackstone AveFRESNOCA93703UNITED STATES OF AMERICAUNITED STATES OF AMERICA36.75891146-119.7902719
LOCATION_HISTORY.csv (Follows CDM format)
location_idrelationship_type_concept_iddomain_identity_idstart_dateend_date
132848114731437631998-01-012020-01-01

Option 2: Coordinates

Sample input files here

location_idlatitudelongitudezipentity_idstart_date
130.353463-81.67493220912019-01-05
229.634219-82.34333260822019-02-14

As with address-based input, including LOCATION.csv and LOCATION_HISTORY.csv enables seamless downstream processing with the linkage container.

Important for auto-generated LOCATION_HISTORY.csv (if not provided as input and only location for index encounter is available):

  • Coordinates can be provided, but rows should include location_id, either address or zip, entity_id (which is same as person_id for a given subject), and start_date (for which visit_start_date can be used as a proxy if no start_date is available).

Option 3: OMOP CDM

TableRequired Columns
personperson_id
visit_occurrencevisit_occurrence_id, visit_start_date, visit_end_date, person_id
locationlocation_id, address_1, address_2, city, state, zip, location_source_value, country_concept_id, country_source_value, latitude, longitude
location_historylocation_id, relationship_type_concept_id, domain_id, entity_id, start_date, end_date

If you have OMOP CDM with required elements already, it can be used to prepare location and location history CSV tables as required by Phase 2.


Usage Guide

For Phase 1 geocoding (latitude/longitude generation), use:

  • Script: Address_to_LOCATION.py
  • Container: prismaplab/exposome-geocoder:1.0.4

This workflow is recommended because it directly prepares files needed for Phase 2 linkage:

  • LOCATION.csv (updated with latitude/longitude and modifier_source_value)
  • LOCATION_HISTORY.csv (maintained in OMOP format)

Step 1: Prepare Input Data

For the recommended workflow, place files in one input folder and run one command.

Preferred input (recommended for all sites):

  • LOCATION.csv in OMOP-style format
  • LOCATION_HISTORY.csv in OMOP-style format

Also supported by Address_to_LOCATION.py:

  • encounter-level CSV files with address columns (for example address or address_1/street, plus city/state/zip)

  • encounter-level CSV files with latitude/longitude (or lat/lon)

Minimum required columns across input files:

  • location_id
  • either address or zip information (for LOCATION.csv generation)

Recommended columns for complete LOCATION_HISTORY.csv auto-generation:

  • entity_id (which is same as person_id for a given subject)
  • start_date (for which visit_start_date can be used as a proxy if no start_date is available)
  • year (used as start_date = YYYY-01-01 only when start date columns are missing)

Input file discovery behavior (for flexibility across sites):

  • LOCATION.csv is preferred when present (filename match is case-insensitive) and is used as the primary input.
  • If LOCATION.csv is not present, the script ingests all other .csv files in the input folder (excluding LOCATION_HISTORY.csv), concatenates them, and processes them as encounter-level input.
  • Arbitrary encounter file names are supported as long as required columns are recognizable (for example address_1/street/address and latitude/longitude or lat/lon).

Folder Structure

  • Place CSV file(s) in a dedicated folder, for example:
    • 📂 input_location/
    • LOCATION.csv
    • LOCATION_HISTORY.csv

⚠️ Only .csv files are supported. Convert .xlsx or other formats before running the tool.

Guidance on Populating LOCATION_HISTORY.csv:

This table links a person to a specific location for a specific time range.

If LOCATION_HISTORY.csv is not provided, Address_to_LOCATION.py auto-generates it from the input rows used to build LOCATION.csv.

  • Default identifiers used by the toolkit during auto-generation:

    • relationship_type_concept_id = 32848 (project default OMOP concept ID for location-person relationship type)
    • domain_id = 1147314 (project default OMOP concept ID corresponding to PERSON domain)
  • entity_id mapping during auto-generation:

    • uses input entity_id when present
    • otherwise uses input person_id
    • if both are missing/blank, script logs an alert and leaves entity_id blank
  • Date mapping during auto-generation:

    • start_date uses input start_date when present, otherwise, uses visit_start_date to impute start_date.
    • if start date fields are missing and year is present, start_date is set to YYYY-01-01
    • end_date uses input end_date when present, otherwise uses visit_end_date to impute end_date.
    • year is not used to populate end_date
    • if start-date values are missing/blank or invalid, script logs an alert and leaves start_date blank

Important validation behavior:

  • The script does not synthesize entity_id values.

  • The script uses year only for start_date fallback (YYYY-01-01) when explicit start date fields are absent.

  • If entity_id or date values are missing/invalid, the script continues execution, reports alert messages with row numbers, and leaves corresponding output fields blank.

  • If you have full residential history: Use the actual move-in (start_date) and move-out (end_date) dates.

  • If you only have location for index ICU encounter and do not have access to previous residential addresses with date stamps as required by location history table, you can use the following logic to populate LOCATION_HISTORY.csv: If linking to specific encounters, set start_date equal to the relevant encounter admission date, that is visit_start_date (in visit_occurance table) . Set end_date to NULL.


Step 2: Run Geocoding for LOCATION Outputs (Primary)

Container: prismaplab/exposome-geocoder:1.0.4
Ensure Docker Desktop is running.

This step uses the Exposome Geocoder container to:

  • preserve any valid existing latitude/longitude provided by your site in LOCATION.csv
  • populate latitude/longitude using addresses
  • impute missing latitude/longitude using staged geocoding fallback that utilizes available zip code information
  • output updated LOCATION.csv for Phase 2
For macOS / Linux / Ubuntu
docker run -it --rm \
-v "$(pwd)":/workspace \
-v /var/run/docker.sock:/var/run/docker.sock \
-e HOST_PWD="$(pwd)" \
-w /workspace \
prismaplab/exposome-geocoder:1.0.4 \
/app/code/Address_to_LOCATION.py -i <input_folder_path>
For Windows
  • Open Command Prompt or PowerShell
  • Run command wsl
  • Execute the same command as above inside your WSL terminal.

Example:

If your files are inside 📂input_location/, run:

docker run -it --rm -v "$(pwd)":/workspace -v /var/run/docker.sock:/var/run/docker.sock -e HOST_PWD="$(pwd)" -w /workspace prismaplab/exposome-geocoder:1.0.4 /app/code/Address_to_LOCATION.py -i input_location
Geocoding Levels Used by Address_to_LOCATION.py

The script assigns the following levels to indicate how latitude and longitude coordinates were obtained:

  • Level 1: Provided coordinates already present in input
  • Level 2: Address-based geocoding
  • Level 3: ZIP9-based geocoding fallback
  • Level 4: ZIP5-based geocoding fallback
  • Failed: No valid coordinate could be assigned

The assigned level is written to modifier_source_value in LOCATION.csv.

Success Rate Reporting

The script writes a geocoding summary report in output/:

  • geocoding_summary_<timestamp>.csv
Legacy / Optional FIPS Workflows

If site needs FIPS-specific outputs in Phase 1, they can still run Address_to_FIPS.py or OMOP_to_FIPS.py using the same container tag (1.0.4).

For OMOP Input (Option 3)

To extract and geocode directly from an OMOP database:

docker run -it --rm \
-v "$(pwd)":/workspace \
-v /var/run/docker.sock:/var/run/docker.sock \
-e HOST_PWD="$(pwd)" \
-w /workspace \
prismaplab/exposome-geocoder:1.0.4 \
/app/code/OMOP_to_FIPS.py \
--user <your_username> \
--password <your_password> \
--server <server_address> \
--port <port_number> \
--database <database_name>

Staged geocoding that imputes latitude and longitude for cases when address is missing, but zip code is available has not been incorporated to this version.

Note on Dependencies (Firewall Warning):

The geocoding scripts attempt to pull Docker images automatically. If you have a strict firewall, you may need to pull these images manually before running the script:

docker pull ghcr.io/degauss-org/geocoder:3.3.0
docker pull ghcr.io/degauss-org/census_block_group:0.6.0

Step 3: Output Structure

After running the geocoder container, the tool generates output files in the output/ folder.

Primary Output (Address_to_LOCATION.py)

Files Generated

  • LOCATION.csv (updated lat/lon + modifier_source_value)
  • LOCATION_HISTORY.csv (OMOP schema preserved)
  • geocoding_summary_<timestamp>.csv (success metrics)
  • geocode_failures_<timestamp>.csv (only when failed records exist)
  • log/address_to_location_<timestamp>.log

Legacy FIPS/Zip Outputs (when using FIPS scripts)

Sample outputs demo/address_files/output

Each input file can produce:

  • <filename>_with_coordinates.csv — input + latitude/longitude
  • <filename>_with_fips.csv — input + FIPS codes

This code has not been updated with latitude and longitude imputations utilizing zip codes and is not recommended to be used, however it may be useful if you need to generate FIPS codes for other purposes.

IMPORTANT TO NOTE

Phase 2 input preparation note: The recommended workflow is to run Address_to_LOCATION.py and use generated LOCATION.csv and LOCATION_HISTORY.csv directly in Phase 2. Ensure your location_id values are consistent between LOCATION.csv and LOCATION_HISTORY.csv before running Phase 2.

Reason Column Values (for failed records):

Possible values include:

  • Street missing
  • City missing
  • State missing
  • Zip missing
  • ZIP9 not found in zip9-fips12 crosswalk
  • ZIP5 not found in HUD crosswalk

OMOP Input (Option 3)

Sample outputs: demo/OMOP/output

Folder Structure

OMOP_data/
├── valid_address/ # Records with address, no lat/lon
├── invalid_lat_lon_address/ # Records missing both address and lat/lon
├── valid_lat_long/ # Records with lat/lon

OMOP_FIPS_result/
├── address/
│ ├── address_with_coordinates.zip # CSVs with lat/lon from address
│ └── address_with_fips.zip # CSVs with FIPS codes
├── latlong/
│ └── latlong_with_fips.zip # CSVs with FIPS from coordinates
├── invalid/ # Usually empty; no usable location data

LOCATION.csv
LOCATION_HISTORY.csv

Step 4: GIS Linkage with PostGIS-Exposure Tool

Purpose:
Spatially joins the lat/lon (and FIPS) from geocoding with geospatial indices (ADI, SVI, AHRQ) and produces EXTERNAL_EXPOSURE.csv.


Prerequisites for GIS Linkage

  • Docker installed.
  • Clone postgis-exposure repository
  • Update LOCATION, LOCATION_HISTORY files to include the geocoded lat/lon from Step 2. Not needed if you included these during the geocoding step
  • Ensure DATA_SRC_SIMPLE.csv and VRBL_SRC_SIMPLE.csv files are available (centrally managed; no edits required).
  • Important: Do not date-shift your LOCATION/LOCATION_HISTORY files before linkage. Date shifting (if used) should occur following this step.

Sample DATA_SRC_SIMPLE.csv and VRBL_SRC_SIMPLE.csv: here


Expected Outputs

  • EXTERNAL_EXPOSURE.csv containing linked indices (ADI, SVI, AHRQ metrics).

GIS Linkage Workflow

  1. Start Postgres/PostGIS container following the instructions in the postgis-exposure repository. Container sequence: start/load database → ingest location tables → run the produce script. First Docker command (prepares the database):

    docker run --rm --name postgis-chorus \
    --env POSTGRES_PASSWORD=dummy \
    --env VARIABLES=134,135,136 \
    --env DATA_SOURCES=1234,5150,9999 \
    -v $(pwd)/test/source:/source \
    -d ghcr.io/chorus-ai/chorus-postgis-exposure:main
    • Replace VARIABLES with the comma-separated list of variable IDs you need from VRBL_SRC_SIMPLE.csv.
    • Replace DATA_SOURCES with the relevant data source IDs (from DATA_SRC_SIMPLE.csv).
  2. ** Generate the external exposure file:**

    docker exec postgis-chorus /app/produce_external_exposure.sh
  3. Output: EXTERNAL_EXPOSURE.csv will appear in your mounted directory (e.g., ./test/source).

Notes & Tips

  • Run these commands in Terminal (Mac) or WSL/PowerShell/Command Prompt on Windows; WSL is more robust for Docker on Windows.
  • If your site needs more variables, expand VARIABLES accordingly.
  • Important: The container may only run successfully once. To rerun, you may need to delete the container and image, then pull the image again.

Step 5: Validate & Inspect Outputs

  • Open EXTERNAL_EXPOSURE.csv. Confirm:
    • Patient ID, lat, lon, FIPS
    • ADI, SVI, AHRQ, and VRBL-coded fields
  • Spot-check a few records for accuracy.
  • If errors:
    • Ensure LOCATION has valid lat/lon/FIPS
    • Confirm VARIABLES and DATA_SOURCES are correct
    • Check mount paths

Step 6: Optional - Site-level Date Shifting

Purpose: Anonymize temporal data while preserving relative timelines.

Guidelines:

  • Apply date shifts locally before upload — do not date-shift prior to GIS linkage.
  • Input: EXTERNAL_EXPOSURE.csv (from Step 4)
  • Output: EXTERNAL_EXPOSURE_date_shifted.csv

See Date Shifting SOP for More Details.


Step 7: Upload & Centralized De-identification

  1. Upload the (optionally date-shifted) EXTERNAL_EXPOSURE.csv to the central repository.
  2. The central team will apply further de-identification.

References & sample files

Geocoding

GIS Linkage

  • Sample files: PostGIS Exposure CSVs
    • Site-specific: LOCATION, LOCATION_HISTORY
    • Centrally managed: DATA_SRC_SIMPLE, VRBL_SRC_SIMPLE

The following office hour sessions provide additional context and demonstrations related to this SOP:

  • [08-07-25] Integration of GIS and SDoH data with OMOP

  • [09-18-25] Processing OMOP location_history table into external_exposure table

  • [09-25-25] End-to-end demo for capturing GIS data with OMOP

  • [10-16-2025] End-to-end demo for capturing GIS data with OMOP or address/latlong

    • Video Recording | Transcript
    • Complete workflow demonstration for GIS data capture and processing based on updated documentation

Appendix

Appendix A: Data Dictionary and Logic

To successfully run Phase 2, your data must match the OMOP CDM definitions below.

These field requirements align with OMOP CDM v6.0 LOCATION and LOCATION_HISTORY expectations.


1. LOCATION Table

Represents physical location or address information.

FieldDescription
location_idThe unique key assigned to a Location. Each instance of a Location in the source data should use this key. [REQUIRED]
address_1First line of the address. [RECOMMENDED, OPTIONAL]
address_2Second line of the address.
cityCity name. [RECOMMENDED, OPTIONAL]
stateState name. [RECOMMENDED, OPTIONAL]
zipZIP code as string. ZIP+4 preferred; ZIP5 accepted. [RECOMMENDED, OPTIONAL]
countyCounty name. [RECOMMENDED, OPTIONAL]
location_source_valueSource text/value for location. [OPTIONAL]
latitudeGeocoded latitude (Float). [OPTIONAL]
longitudeGeocoded longitude (Float). [OPTIONAL]

Notes for this toolkit:

  • The generated LOCATION.csv may also include OMOP-compatible country columns (country_concept_id, country_source_value) and geocoding provenance (modifier_source_value).

2. LOCATION_HISTORY Table

Stores relationships between persons and geographic locations over time.

FieldDescription
location_idReferences the location_id in the LOCATION table. [REQUIRED]
relationship_type_concept_idOMOP concept ID for location-person relationship type. Defaults to 32848. [REQUIRED]
domain_idDomain of the entity. For this toolkit output, this is emitted as OMOP concept id 1147314 (PERSON domain concept). [REQUIRED]
entity_idUnique identifier for the entity; should be person_id. [REQUIRED]
start_dateDate the relationship started. [REQUIRED]
end_dateDate the relationship ended. [RECOMMENDED, OPTIONAL]

Notes for this toolkit:

  • entity_id should align with OMOP PERSON.person_id when domain_id is PERSON.
  • If LOCATION_HISTORY.csv is not supplied, the script auto-generates it from available input fields.
  • Missing values (entity_id/person_id, start_date/visit_start_date) trigger an alert, the script continues, and corresponding fields remain blank.
  • If only year is provided, the script sets start_date to YYYY-01-01 and does not infer end_date from year.

3. EXTERNAL_EXPOSURE Table

After Phase 2 execution, the pipeline generates the external_exposure table with the columns below.

VariableDescription
external_exposure_idUnique row identifier for the exposure record.
location_idForeign key linking to the input LOCATION.csv file.
person_idForeign key linking to entity_id in the input LOCATION_HISTORY.csv file.
exposure_start_dateStart date of the exposure event (calculated overlap).
exposure_end_dateEnd date of the exposure event.
exposure_source_valueName of the environmental variable linked.
value_as_numberNumerical value of the environmental variable.
unit_concept_idOMOP Concept ID representing the unit of measure.
exposure_concept_idOMOP Concept ID representing the environmental variable.
exposure_type_concept_idOMOP Concept ID for the type of exposure.
value_as_concept_idOMOP Concept ID for categorical results.
modifier_source_valueThis field will be used to provide level that explains information used for coordinate generation.

Note: This table reflects the exposure data generated as output of Phase 2.


4. GEOCODING_SUMMARY Report (Phase 1 output)

The geocoding_summary_<timestamp>.csv report provides record-level completion metrics for Phase 1 geocoding.

ColumnDescription
total_recordsTotal number of rows processed in LOCATION.csv.
records_with_coordinatesNumber of rows with valid latitude and longitude after geocoding.
records_without_coordinatesNumber of rows that still do not have valid coordinates.
success_rate_percentPercent of rows with valid coordinates (records_with_coordinates / total_records * 100).
level1_providedCount of rows where input coordinates were already valid.
level2_addressCount of rows geocoded from address-level input.
level3_zip9Count of rows geocoded using ZIP9 fallback.
level4_zip5Count of rows geocoded using ZIP5 fallback.
failedCount of rows with unresolved geocoding failures.

5. GEOCODE_FAILURES Report (Phase 1 output)

The geocode_failures_<timestamp>.csv report includes only rows that remain unresolved after staged geocoding.

ColumnDescription
location_idLocation identifier associated with the failed geocoding row.
address_1Normalized primary street/address line available at failure time.
address_2Normalized secondary address/unit line available at failure time.
cityNormalized city available at failure time.
stateNormalized state available at failure time.
zipNormalized ZIP5 available at failure time.
geocode_levelFinal geocoding status (failed).
geocode_reasonAggregated reason(s) indicating why geocoding could not be completed.

Appendix B: Geocoding Workflow

This guide outlines the scripts, workflows, and Docker based DeGAUSS toolkit used to generate latitude and longitude coordinates from patient data. The process follows a two step geocoding workflow powered by DeGAUSS and executed locally via Docker containers.

Method: DeGAUSS Toolkit (Docker-based)

DeGAUSS consists of two Docker containers:

  1. Geocoder (3.3.0) — Converts address to latitude/longitude
  2. Census Block Group (0.6.0) — Converts latitude/longitude to Census Tract FIPS codes
StepPurposeDocker Image
1Address → Coordinatesghcr.io/degauss-org/geocoder:3.3.0
2Coordinates → FIPSghcr.io/degauss-org/census_block_group:0.6.0

DeGAUSS Docker Commands (Executed Internally)

# Step 1: Get Coordinates from Address
docker run --rm -v "ABS_OUTPUT_FOLDER:/tmp" \
ghcr.io/degauss-org/geocoder:3.3.0 \
/tmp/<your_preprocessed_input.csv> <threshold>

# Step 2: Get FIPS from Coordinates
docker run --rm -v "ABS_OUTPUT_FOLDER:/tmp" \
ghcr.io/degauss-org/census_block_group:0.6.0 \
/tmp/<your_coordinate_output.csv> <year>

Replace values:

  • ABS_OUTPUT_FOLDER → absolute path to your output directory
  • <threshold> → numeric value (e.g., 0.7)
  • <year> → either 2010 or 2020

Script Highlights

While our toolkit supports both LOCATION generation and FIPS workflows, Phase 2 requires latitude and longitude coordinates in LOCATION-based files.

Address_to_LOCATION.py Logic

This script is the recommended Phase 1 workflow:

  • Reads LOCATION.csv (or compatible encounter-level CSV inputs)
  • Preserves valid existing latitude/longitude values
  • Uses staged fallback to fill missing coordinates:
    • address geocoding
    • ZIP9 fallback
    • ZIP5 fallback
  • Writes:
    • LOCATION.csv with updated coordinates and modifier_source_value
    • LOCATION_HISTORY.csv in OMOP format
    • geocoding summary and failure reports
Address_to_FIPS.py Logic

This script handles CSV-based input:

  • Reads CSV files
  • Normalizes address or uses lat/lon
  • Runs DeGAUSS Docker container to generate:
    • Latitude/Longitude (via ghcr.io/degauss-org/geocoder)
    • FIPS codes(via ghcr.io/degauss-org/census_block_group)
  • Packages outputs into ZIP
OMOP_to_FIPS.py Logic

This script integrates directly with OMOP CDM:

  • Extracts OMOP CDM data
  • Categorizes into valid/invalid address or coordinates
  • Executes FIPS generation (same as CSV workflow)
  • Packages outputs into ZIP